ABSTRACT
Hair follicle nevus (HFN) is a rare, benign, follicular hamartoma that most frequently presents as a congenital nodule on the face. We experienced a rare case of HFN on the neck of a 14-year-old boy and performed a pilot immunohistochemical study with cytokeratin 19 (CK19) to compare the staining pattern of hair follicles in HFN and its differential diagnoses, accessory tragus, cervical chondrocutaneous branchial remnants (CCBR) and trichofolliculoma. With hematoxylin and eosin stain, HFN showed numerous tiny hair follicles in the dermis with several sebaceous and eccrine glands, and perifollicular fibrous thickening. With CK19 stain, some hair follicles in HFN and CCBR showed positive expression, a few hair follicles in accessory tragus showed weak expression, and no hair follicles in trichofolliculoma showed expression. The present report supports the view that HFN, accessory tragus and CCBR are within the same spectrum of hamartomas.
Subject(s)
Adolescent , Humans , Male , Dermis , Diagnosis, Differential , Eccrine Glands , Eosine Yellowish-(YS) , Hair Follicle , Hair , Hamartoma , Hematoxylin , Keratin-19 , Neck , NevusABSTRACT
No abstract available.
ABSTRACT
Cervical chondrocutaneous branchial remnants are rare and one of several maformations resulting from abnormal development of the branchial apparatus. These lesions are usually located over or near the insertions of the sternocleidomastoid muscles in the lower neck. It is important to recognize that they may be a visible marker for other malformations and/or anomalies. Treatment is complete surgical removal as promptly as possible in order to get an exact histopathological diagnosis. In this article, we report a rare case of cervical chondrocutaneous branchial remnants and some reviews of the literature.